E-HERBARIA

  • Name : Brahmi
  • English Name :Thyme leaved Gratiola
  • Scientific Name :Bacopa monnieri

 

Habitat:

The herb is found throughout India in wet and damp places.

 

Morphology Description (Habit):

A glabrous, succulent, small, prostrate or creeping annual herb with thin, wiry, small, branched and creamish-yellow root; the stem is thin, green or purplish green in colour. The leaves are simple, opposite, decussate, green, sessile, 1-2 cm long, obovate-oblong, and the flowers are small, axillary and solitary with 6-30 mm long pedicels.

 

Parts Used:

Whole Plant

 

Phytochemistry:

Alkaloids ? primarily Bacosides.

 

As per Ayurveda:

           Rasa (Taste)                 : Sweet, Bitter and Astringent

           Guna (Property)           : Light

           Veerya (Potency)         : Cold

           Vipaka (End Result)      : Sweet

 

Pharmacological Actions:

As per Ayurveda, Brahmi is Vatakaphahara, Medhya and Rasayana.

The primary pharmacological actions of this herbal nootropic and cognitive-enhancer are summarized as under:

 

Central Nervous System: 

i. Possesses excellent Cognitive-enhancing functions - Improves memory and learning abilities.2

ii. Exerts neuroprotective effect and is useful in Alzheimer?s disease and dementia related Cognitive decline.3

iii. Increases Cerebral Blood Flow, further supporting its Pro-cognitive effect.4

iv. Allays anxiety.

 

Digestive System : 

i. Exerts hepatoprotective activity.

 

Endocrynal System: 

i. Bacosine, a triterpene present in Brahmi possesses significant antihyperglycaemic activity.

 

Cardiovascular System : 

i. Releases Nitric Oxide from endothelium and acts on Vascular smooth muscles, acting as an efficacious Antihypertensive and Vasodilator.5

 

Skin and Hair : 

i. Helps in healing of wounds.

 

Others : 

i. Endows significant Immunostimulatory effect.6

ii. Possesses anti-tumor activity.

 

Indications:

Learning, Concentration and Memory Deficits

Prevention against age related neuroinflammation and allied disorders, such as Dementia and Alzheimer?s disease

Disturbed Sleep and Lack of Sleep

Stress, anxiety and fatigue, allied lowered Immunity

(As an adjuvant in) Hypertension, Type-2 Diabetes mellitus, Parkinsonism and Epilepsy

 

References:

1. The Ayurvedic Pharmacopoeia of India, Part-1, Volume ? 2.

2. Pase MP, Kean J, Sarris J, et al. The Cognitive Enhancing effects of Bacopa monnieri: A Systemic review of Randomized, Controlled Human Clinical Trials. Journal of Alternative and Complementary Medicine. 2012; 18(7): 647-52.

3. Saini N, Singh D, Sandhir R. Neuroprotective Effects of Bacopa monnieri in Experimental model of Dementia. Neurochemical Research. 2012; 37(9): 1928-37.

4. Kamkaew N, Norman Scholfield C, et al. Bacopa monnieri increases Cerebral Blood Flow in Rat independent of Blood Pressure. Phytotherapy Research. 2012; PMID: 22447676.

5. Kamkaew N, Norman Scholfield C, et al. Bacopa monnieri and its constituents is hypotensive in anaesthetised rats and vasodilator in various artery types. Journal of Ethnopharmacology. 2011; 137(1): 790-5.

6. Yamada K, Hung P, Park TK, et al. A comparison of the Immunostimulatory effects of the medicinal herbs Echinacea, Ashwagandha and Brahmi. Journal of Ethnopharmacology. 2011; 137(1): 231-5.

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